Capsaicin is also derived from chili peppers, and when purified works at a pharmacological level. Purified capsaicin is the active ingredient in Zostrix.

Directions

1. Apply Zostrix 3 to 4 times a day, every day.

    Apply just enough to cover the affected area (a small fingertip is usually enough).

2. Massage Zostrix cream into the skin on the front, back and sides of the affected area until no residue remains.

3. Unless treating hands, always wash hands thoroughly with soap and water after the application and avoid contact with sensitive areas, such as eyes.

Wash hands immediately after application (unless treating hands), and:

• Do not apply Zostrix to broken, open or irritated skin.
• Do not apply heat pads or have a hot shower immediately after application.
• Avoid bandaging the area following application.
• Avoid touching the eyes, mouth or other sensitive areas.

For best results, little and often is the rule to follow.

Application of Zostrix sometimes causes a burning sensation.

The heat, discomfort or burning sensation experienced by some patients upon application is related to the way Zostrix works. Do not be concerned. This sensation is thought to be related to the initial release of Substance P and discomfort generally diminishes after the first few days of continued use. Remember, Zostrix works gradually so pain relief may take up to 4-6 weeks.